Prince Frederik of Luxembourg, the youngest son of Prince Robert and Princess Julie of Nassau, passed away on March 1, 2025, at the age of 22. He succumbed to POLG mitochondrial disease, a rare genetic disorder that progressively impairs the body’s ability to produce energy, leading to multiple organ dysfunction and failure. citeturn0search3
Early Life and Diagnosis Prince Frederik
Born in Paris, Frederik spent his childhood in London and Geneva, attending various international schools. At 14, he was diagnosed with POLG mitochondrial disease, a condition that affects approximately 300 million people worldwide. Despite the challenges, Frederik maintained a positive outlook and a strong sense of humor throughout his life. citeturn0news12
Advocacy and the POLG Foundation Prince Frederik
Refusing to let his diagnosis define him, Frederik founded the POLG Foundation to raise awareness and fund research for treatments and a cure. The foundation played a pivotal role in advancing scientific understanding of the disease and supporting affected individuals. Frederik’s dedication extended to developing research models and collaborating internationally to facilitate studies on POLG. citeturn0search3
Final Moments Prince Frederik
In his final days, Frederik’s family gathered around him. Despite physical limitations, he communicated his love and shared moments of levity, leaving a lasting impression on his loved ones. His father, Prince Robert, described him as a “superhero,” highlighting Frederik’s resilience and impact. citeturn0search3
Frederik’s journey was marked by courage, advocacy, and an unwavering spirit. His efforts through the POLG Foundation continue to influence research and support for those affected by the disease. The family’s call for support of the foundation in Frederik’s memory ensures that his legacy endures, inspiring others to contribute to the fight against POLG mitochondrial disease. citeturn0search3
Legacy Prince Frederik
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